MolNFT v1 · #125687 · protein

Solution structure of the N-terminal domain of ogataea polymorpha telomerase reverse transcriptase

5LGF: “Solution structure of the N-terminal domain of ogataea polymorpha telomerase reverse transcriptase”. Solution nmr, 1 pocket (best druggability 0.58). MolNFT v1 #125687 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5LGF
Type: protein
Length: 159 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Telomerase reverse transcriptase
UniProt: R4IT35
Pockets: 1 · best druggability 0.58

Structure

solution nmr · 1 distinct chain · 43% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Telomerase reverse transcriptase	protein	159	43% helix, 8% strand	R4IT35

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	238	0.58	0.79	32	empty

Compared structures

5LGF · Solution structure of the N-terminal domain of Ogataea polymorpha telomerase reverse… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt R4IT35
Elsewhere: RCSB PDB 5LGF · PDBe 5LGF · UniProt R4IT35

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