MolNFT v1 · #12535 · protein
CA2+-ATPase in the E2 state
1KJU · SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 1A: “CA2+-ATPase in the E2 state”. Electron microscopy, 11 pockets (best druggability 0.83). MolNFT v1 #12535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1KJU
- Type
- protein
- Length
- 994 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 1A
- EC
- 3.6.3.8
- UniProt
- P04191
- Pockets
- 11 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 42% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 1A (EC 3.6.3.8) | protein | 994 | 42% helix, 14% strand | P04191 |
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 395 | 0.83 | 0.91 | 46 | empty |
| 2 | 89 | 0.77 | 0.98 | 31 | empty |
| 3 | 892 | 0.75 | 0.78 | 98 | empty |
| 4 | 217 | 0.65 | 0.83 | 30 | empty |
| 5 | 59 | 0.61 | 0.92 | 18 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04191
- Elsewhere: RCSB PDB 1KJU · PDBe 1KJU · UniProt P04191
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