MolNFT v1 · #125321 · protein

Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 ångström, spacegroup P4(3)22

5L5N · Plexin-A4: “Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 ångström, spacegroup P4(3)22”. X-ray diffraction, 12 pockets (best druggability 0.69). MolNFT v1 #125321 on GenesisL1: 3D structure, binding sites…

PDB: 5L5N
Type: protein
Length: 915 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plexin-A4
UniProt: Q80UG2
Pockets: 12 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plexin-A4	protein	915	8% helix, 38% strand	Q80UG2

Pockets

12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	480	0.69	0.80	38	empty
2	80	0.69	0.94	25	empty
3	241	0.60	0.80	28	empty
4	112	0.50	0.81	21	empty
5	127	0.49	0.80	22	empty

Modifications

Observed in the structure: 21 disulfide (disulfide).

Compared structures

5L5N · Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 angstrom… · the same entry in another collection · chain A against A, TM-score 1.00
Q80UG2 · AlphaFold monomer V2.0 prediction for plexin-A4 (Q80UG2) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80UG2
Elsewhere: RCSB PDB 5L5N · PDBe 5L5N · UniProt Q80UG2

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