MolNFT v1 · #124946 · protein

Crystal structure of trypsin activated CRY6AA

5KUC · Pesticidal crystal protein CRY6AA: “Crystal structure of trypsin activated CRY6AA”. X-ray diffraction, 3 pockets (best druggability 0.55). MolNFT v1 #124946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KUC
Type: protein
Length: 402 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pesticidal crystal protein CRY6AA
UniProt: Q45757
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 73% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pesticidal crystal protein CRY6AA	protein	402	73% helix, 2% strand	Q45757

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.55	0.90	21	empty
2	77	0.42	0.80	15	empty
3	84	0.34	0.75	15	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5KUC · Crystal structure of trypsin activated Cry6Aa · the same entry in another collection · chain A against A, TM-score 1.00
Q45757 · AlphaFold monomer V2.0 prediction for pesticidal crystal protein CRY6AA (Q45757) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q45757
Elsewhere: RCSB PDB 5KUC · PDBe 5KUC · UniProt Q45757

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