MolNFT v1 · #124740 · protein
Structure of a core papain-like protease of MERS coronavirus with utility for structure-based drug design
5KO3 · ORF1A: “Structure of a core papain-like protease of MERS coronavirus with utility for structure-based drug design”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.31). MolNFT v1 #124740 on GenesisL1: 3D structure…
- PDB
- 5KO3
- Type
- protein
- Length
- 257 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ORF1A
- UniProt
- A0A023J538
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ORF1A | protein | 257 | 28% helix, 39% strand | A0A023J538 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.31 | 0.76 | 16 | empty |
Modifications
Observed in the structure: 1 modified (artifact).
Compared structures
- 5KO3 · Structure of a Core Papain-like Protease of MERS Coronavirus with utility for… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A023J538
- Elsewhere: RCSB PDB 5KO3 · PDBe 5KO3 · UniProt A0A023J538
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