MolNFT v1 · #124700 · protein

Ctx-M-9 beta lactamase mutant - T165W

5KMU · Beta-lactamase: “Ctx-M-9 beta lactamase mutant - T165W”. X-ray diffraction, 2 ligands (PO4, CL), 1 pocket (best druggability 0.30). MolNFT v1 #124700 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KMU
Type: protein
Length: 261 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: Q9L5C8
Ligands: PO4, CL
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	261	44% helix, 19% strand	Q9L5C8

Ligands and binding sites

PO4 · Phosphate ion · ion · 4 copies · chains A
CL · Chloride ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.30	0.75	17	PO4

Compared structures

5KMU · CTX-M-9 beta lactamase mutant - T165W · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9L5C8
Elsewhere: RCSB PDB 5KMU · PDBe 5KMU · UniProt Q9L5C8

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