MolNFT v1 · #124599 · protein
Crystal structure of coleus blumei hct
5KJV · Hydroxycinnamoyl transferase: “Crystal structure of coleus blumei hct”. X-ray diffraction, 11 pockets (best druggability 0.84). MolNFT v1 #124599 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5KJV
- Type
- protein
- Length
- 854 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hydroxycinnamoyl transferase
- EC
- 2.3.1.133
- UniProt
- E8ZAP2
- Pockets
- 11 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hydroxycinnamoyl transferase (EC 2.3.1.133) | protein | 427 | 32% helix, 24% strand | E8ZAP2 |
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 942 | 0.84 | 0.85 | 87 | empty |
| 2 | 888 | 0.83 | 0.85 | 70 | empty |
| 3 | 252 | 0.68 | 0.84 | 37 | empty |
| 4 | 111 | 0.48 | 0.80 | 20 | empty |
| 5 | 70 | 0.45 | 0.82 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 746 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 5KJV · Crystal structure of Coleus blumei HCT · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E8ZAP2
- Elsewhere: RCSB PDB 5KJV · PDBe 5KJV · UniProt E8ZAP2
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