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MolNFT v1 · #124339 · protein

The structure of SAV2435 bound to ethidium bromide

5KCB · SA2223 protein: “The structure of SAV2435 bound to ethidium bromide”. X-ray diffraction, 2 ligands (ET, SO4), 1 pocket (best druggability 0.58). MolNFT v1 #124339 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5KCB
Type
protein
Length
165 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
SA2223 protein
UniProt
A0A0H3JRN6
Ligands
ET, SO4
Pockets
1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 36% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASA2223 proteinprotein16528% helix, 36% strandA0A0H3JRN6

Ligands and binding sites

  • ET · Ethidium · ligand · chains A
  • SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13130.580.7640ET

Modifications

Observed in the structure: 1 isopeptide (isopeptide).

Compared structures

  • 5KCB · The structure of SAV2435 bound to ethidium bromide · the same entry in another collection · chain A against A, TM-score 1.00

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