MolNFT v1 · #124335 · protein
Crystal structure of CBLN1 (VAL55-GLY58 deletion mutant)
5KC7 · Cerebellin-1: “Crystal structure of CBLN1 (VAL55-GLY58 deletion mutant)”. X-ray diffraction, 7 pockets (best druggability 0.77). MolNFT v1 #124335 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5KC7
- Type
- protein
- Length
- 540 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cerebellin-1
- UniProt
- P23435
- Pockets
- 7 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Cerebellin-1 | protein | 135 | 4% helix, 53% strand | P23435 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 325 | 0.77 | 0.89 | 60 | empty |
| 2 | 650 | 0.71 | 0.78 | 70 | empty |
| 3 | 56 | 0.69 | 0.98 | 33 | empty |
| 4 | 141 | 0.48 | 0.77 | 21 | empty |
| 5 | 54 | 0.44 | 0.83 | 13 | empty |
Interfaces
5 interfaces between chains.
- A–B · 823 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 819 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 817 Ų buried · 5 hydrogen bonds · protein-protein
- B–D · 301 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 37 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23435
- Elsewhere: RCSB PDB 5KC7 · PDBe 5KC7 · UniProt P23435
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