MolNFT v1 · #124095 · protein

Hdd domain from human DDI2

5K57 · Protein DDI1 homolog 2: “Hdd domain from human DDI2”. Solution nmr, 2 pockets (best druggability 0.48). MolNFT v1 #124095 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5K57
Type: protein
Length: 98 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein DDI1 homolog 2
UniProt: Q5TDH0
Pockets: 2 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 52% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein DDI1 homolog 2	protein	98	52% helix, 0% strand	Q5TDH0

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.48	0.77	25	empty
2	95	0.33	0.73	18	empty

Compared structures

5K57 · HDD domain from human Ddi2 · the same entry in another collection · chain A against A, TM-score 1.00
Q5TDH0 · AlphaFold monomer V2.0 prediction for protein DDI1 homolog 2 (Q5TDH0) · a predicted model of the same protein · chain A against A, TM-score 0.62

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5TDH0
Elsewhere: RCSB PDB 5K57 · PDBe 5K57 · UniProt Q5TDH0

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