MolNFT v1 · #124081 · protein
Three-dimensional structure of L-threonine 3-dehydrogenase from trypanosoma brucei refined to 2.1 ångströms
5K4T: “Three-dimensional structure of L-threonine 3-dehydrogenase from trypanosoma brucei refined to 2.1 ångströms”. X-ray diffraction, 1 pocket (best druggability 0.73). MolNFT v1 #124081 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5K4T
- Type
- protein
- Length
- 321 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-threonine 3-dehydrogenase
- EC
- 1.1.1.103
- UniProt
- Q7YW97
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-threonine 3-dehydrogenase (EC 1.1.1.103) | protein | 321 | 45% helix, 15% strand | Q7YW97 |
Ligands and binding sites
- GOL · Glycerol · additive · 8 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 475 | 0.73 | 0.82 | 52 | empty |
Compared structures
- 5K4T · Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7YW97
- Elsewhere: RCSB PDB 5K4T · PDBe 5K4T · UniProt Q7YW97
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