MolNFT v1 · #123904 · protein
NMR structure of foldswitch-stablized kaib in complex with pseudo receiver domain of cika from thermosynechococcus elongatus
5JYV · Two-component sensor histidine kinase: “NMR structure of foldswitch-stablized kaib in complex with pseudo receiver domain of cika from…”. Solution nmr, 2 pockets (best druggability 0.45). MolNFT v1 #123904 on GenesisL1: 3D…
- PDB
- 5JYV
- Type
- protein
- Length
- 223 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two-component sensor histidine kinase; Circadian clock protein kaib
- UniProt
- Q8DKG0, Q79V61
- Pockets
- 2 · best druggability 0.45
Structure
solution nmr · 2 distinct chains · 35% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two-component sensor histidine kinase | protein | 117 | 35% helix, 21% strand | Q8DKG0 |
| B | Circadian clock protein kaib | protein | 106 | 36% helix, 21% strand | Q79V61 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 105 | 0.45 | 0.79 | 22 | empty |
| 2 | 60 | 0.40 | 0.80 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1171 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 5JYV · NMR structure of foldswitch-stablized KaiB in complex with pseudo receiver domain of CikA… · the same entry in another collection · chain A against A, TM-score 1.00
- Q79V61 · AlphaFold monomer V2.0 prediction for circadian clock protein kaib (Q79V61) · a predicted model of the same protein · chain B against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8DKG0
- Every structure of UniProt Q79V61
- Elsewhere: RCSB PDB 5JYV · PDBe 5JYV · UniProt Q8DKG0 · UniProt Q79V61
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