MolNFT v1 · #123649 · protein

The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of francisella tularensis subsp. tularensis schu S4 in complex with ADP

5JQW · N5-carboxyaminoimidazole ribonucleotide synthase: “The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of francisella tularensis…”. X-ray diffraction, 1 ligand (ADP), 1 pocket (best druggability 0.74).…

PDB: 5JQW
Type: protein
Length: 365 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: N5-carboxyaminoimidazole ribonucleotide synthase
EC: 6.3.4.18
UniProt: Q5NGE8
Ligands: ADP
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18)	protein	365	35% helix, 28% strand	Q5NGE8

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	763	0.74	0.79	64	ADP

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

5JQW · The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5NGE8
Elsewhere: RCSB PDB 5JQW · PDBe 5JQW · UniProt Q5NGE8

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