MolNFT v1 · #123611 · protein
Structure of the zika virus NS3 helicase domain
5JPS: “Structure of the zika virus NS3 helicase domain”. X-ray diffraction, 2 pockets (best druggability 0.81). MolNFT v1 #123611 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5JPS
- Type
- protein
- Length
- 430 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NS3 helicase
- EC
- 3.6.4.13
- UniProt
- Q32ZE1
- Pockets
- 2 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NS3 helicase (EC 3.6.4.13) | protein | 430 | 33% helix, 19% strand | Q32ZE1 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 904 | 0.81 | 0.83 | 88 | empty |
| 2 | 320 | 0.60 | 0.78 | 35 | empty |
Compared structures
- 5JPS · Structure of the Zika Virus NS3 Helicase Domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q32ZE1
- Elsewhere: RCSB PDB 5JPS · PDBe 5JPS · UniProt Q32ZE1
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