MolNFT v1 · #123362 · protein
Crystal structure of zika virus envelope protein
5JHM: “Crystal structure of zika virus envelope protein”. X-ray diffraction, 9 pockets (best druggability 0.57). MolNFT v1 #123362 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5JHM
- Type
- protein
- Length
- 781 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope protein
- Pockets
- 9 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelope protein | protein | 391 | 8% helix, 49% strand | — |
| B | Envelope protein | protein | 390 | 8% helix, 51% strand | — |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 197 | 0.57 | 0.80 | 27 | empty |
| 2 | 239 | 0.55 | 0.77 | 27 | empty |
| 3 | 176 | 0.49 | 0.77 | 38 | empty |
| 4 | 163 | 0.47 | 0.77 | 31 | empty |
| 5 | 70 | 0.33 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1193 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 disulfide (disulfide).
Compared structures
- 5JHM · Crystal structure of Zika virus Envelope protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5JHM · PDBe 5JHM
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