MolNFT v1 · #123318 · protein

Crystal structure of the rice topless related protein 2 (TPR2) N- terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant

5JGC · Protein TPR1: “Crystal structure of the rice topless related protein 2 (TPR2) N- terminal topless domain (1-209) L111A…”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.51). MolNFT v1 #123318 on GenesisL1: 3D…

PDB: 5JGC
Type: protein
Length: 199 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein TPR1
UniProt: Q5NBT9
Ligands: ZN
Pockets: 2 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 65% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein TPR1	protein	199	65% helix, 0% strand	Q5NBT9

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	203	0.51	0.76	31	empty
2	68	0.32	0.74	16	empty

Compared structures

5JGC · Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain… · the same entry in another collection · chain A against A, TM-score 1.00
Q5NBT9 · AlphaFold monomer V2.0 prediction for protein TPR1 (Q5NBT9) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5NBT9
Elsewhere: RCSB PDB 5JGC · PDBe 5JGC · UniProt Q5NBT9

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