MolNFT v1 · #123231 · protein
E73V mutant of the human voltage-dependent anion channel
5JDP · Voltage-dependent anion-selective channel protein 1: “E73V mutant of the human voltage-dependent anion channel”. Solution nmr, 3 pockets (best druggability 0.67). MolNFT v1 #123231 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5JDP
- Type
- protein
- Length
- 285 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Voltage-dependent anion-selective channel protein 1
- UniProt
- P21796
- Pockets
- 3 · best druggability 0.67
Structure
solution nmr · 1 distinct chain · 4% helix, 63% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Voltage-dependent anion-selective channel protein 1 | protein | 285 | 4% helix, 63% strand | P21796 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 670 | 0.67 | 0.76 | 83 | empty |
| 2 | 189 | 0.47 | 0.75 | 27 | empty |
| 3 | 93 | 0.33 | 0.73 | 16 | empty |
Compared structures
- 5JDP · E73V mutant of the human voltage-dependent anion channel · the same entry in another collection · chain A against A, TM-score 1.00
- P21796 · AlphaFold monomer V2.0 prediction for voltage-dependent anion- selective channel protein… · a predicted model of the same protein · chain A against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21796
- Elsewhere: RCSB PDB 5JDP · PDBe 5JDP · UniProt P21796
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