MolNFT v1 · #123048 · protein
Crystal structure of glycoprotein C from puumala virus in the post- fusion conformation (pH 6.0)
5J81 · Envelopment polyprotein: “Crystal structure of glycoprotein C from puumala virus in the post- fusion conformation (pH 6.0)”. X-ray diffraction, 3 ligands (NAG, BMA, SO4), 2 pockets (best druggability 0.56). MolNFT v1 #123048 on…
- PDB
- 5J81
- Type
- protein
- Length
- 411 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelopment polyprotein
- UniProt
- P41266
- Ligands
- NAG, BMA, SO4
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelopment polyprotein | protein | 411 | 6% helix, 53% strand | P41266 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- BMA · beta-D-mannopyranose · sugar
- SO4 · Sulfate ion · ion · chains A
- P33 · 3,6,9,12,15,18-hexaoxaicosane-1,20-diol · additive · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.56 | 0.74 | 52 | SO4 |
| 2 | 258 | 0.53 | 0.76 | 37 | empty |
Modifications
Observed in the structure: 12 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5J81 · Crystal structure of Glycoprotein C from Puumala virus in the post-fusion conformation… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41266
- Elsewhere: RCSB PDB 5J81 · PDBe 5J81 · UniProt P41266
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