MolNFT v1 · #122930 · protein
Crystal structure of udp-glucose pyrophosporylase / UTP-glucose-1- phosphate uridylyltransferase from burkholderia xenovorans
5J49 · UTP--glucose-1-phosphate uridylyltransferase: “Crystal structure of udp-glucose pyrophosporylase / UTP-glucose-1- phosphate uridylyltransferase from…”. X-ray diffraction, 1 ligand (SO4), 7 pockets (best druggability 0.60). MolNFT v1…
- PDB
- 5J49
- Type
- protein
- Length
- 584 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UTP--glucose-1-phosphate uridylyltransferase
- EC
- 2.7.7.9
- UniProt
- Q13WC0
- Ligands
- SO4
- Pockets
- 7 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) | protein | 292 | 40% helix, 24% strand | Q13WC0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 355 | 0.60 | 0.77 | 36 | empty |
| 2 | 360 | 0.59 | 0.77 | 36 | empty |
| 3 | 359 | 0.59 | 0.76 | 45 | empty |
| 4 | 361 | 0.59 | 0.76 | 45 | empty |
| 5 | 107 | 0.41 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 912 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 5J49 · Crystal structure of UDP-glucose pyrophosporylase / UTP-glucose-1-phosphate… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13WC0
- Elsewhere: RCSB PDB 5J49 · PDBe 5J49 · UniProt Q13WC0
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