GL1X · GenesisL1 explorer

MolNFT v1 · #122911 · protein

Crystal structure of S. pombe DCP1:EDC1 mRNA decapping complex

5J3Q · MRNA-decapping enzyme subunit 1: “Crystal structure of S. pombe DCP1:EDC1 mRNA decapping complex”. X-ray diffraction. MolNFT v1 #122911 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5J3Q
Type
protein
Length
279 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
MRNA-decapping enzyme subunit 1; EDC1
UniProt
Q9P805, Q10108

Structure

x-ray diffraction · 3 distinct chains · 26% helix, 40% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, CMRNA-decapping enzyme subunit 1protein12527% helix, 50% strandQ9P805
BEDC1protein1421% helix, 0% strandQ10108
DEDC1protein1520% helix, 0% strandQ10108

Interfaces

4 interfaces between chains.

  • A–B · 708 Ų buried · 8 hydrogen bonds · protein-protein
  • C–D · 618 Ų buried · 7 hydrogen bonds · protein-protein
  • B–C · 117 Ų buried · 0 hydrogen bonds · protein-protein
  • A–C · 75 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

  • 5J3Q · Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex · the same entry in another collection · chain D against D, TM-score 1.00
  • Q9P805 · AlphaFold monomer V2.0 prediction for mRNA-decapping enzyme subunit 1 (Q9P805) · a predicted model of the same protein · chain A against A, TM-score 0.97
  • Q10108 · AlphaFold monomer V2.0 prediction for uncharacterized protein C18G6.09C (Q10108) · a predicted model of the same protein · chain B against A, TM-score 0.48

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