MolNFT v1 · #122838 · protein
Structure of the spectrin repeats 7, 8, and 9 of the plakin domain of plectin
5J1I: “Structure of the spectrin repeats 7, 8, and 9 of the plakin domain of plectin”. X-ray diffraction, 4 pockets (best druggability 0.62). MolNFT v1 #122838 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5J1I
- Type
- protein
- Length
- 691 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plectin
- UniProt
- Q15149
- Pockets
- 4 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 90% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plectin | protein | 346 | 90% helix, 0% strand | Q15149 |
| B | Plectin | protein | 345 | 90% helix, 0% strand | Q15149 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 459 | 0.62 | 0.76 | 64 | empty |
| 2 | 262 | 0.48 | 0.73 | 38 | empty |
| 3 | 230 | 0.45 | 0.73 | 18 | empty |
| 4 | 100 | 0.44 | 0.79 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 681 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 5J1I · Structure of the spectrin repeats 7, 8, and 9 of the plakin domain of plectin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15149
- Elsewhere: RCSB PDB 5J1I · PDBe 5J1I · UniProt Q15149
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