MolNFT v1 · #122785 · protein
Crystal structure of the legionella pneumophila effector protein ravz - F222
5IZV · Uncharacterized protein ravz: “Crystal structure of the legionella pneumophila effector protein ravz - F222”. X-ray diffraction, 7 pockets (best druggability 0.51). MolNFT v1 #122785 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5IZV
- Type
- protein
- Length
- 745 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein ravz
- UniProt
- Q5ZUV9
- Pockets
- 7 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein ravz | protein | 376 | 43% helix, 19% strand | Q5ZUV9 |
| B | Uncharacterized protein ravz | protein | 369 | 43% helix, 19% strand | Q5ZUV9 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.51 | 0.75 | 32 | empty |
| 2 | 119 | 0.49 | 0.80 | 24 | empty |
| 3 | 91 | 0.48 | 0.82 | 17 | empty |
| 4 | 95 | 0.34 | 0.74 | 20 | empty |
| 5 | 79 | 0.32 | 0.75 | 15 | empty |
Compared structures
- 5IZV · Crystal structure of the legionella pneumophila effector protein RavZ - F222 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZUV9
- Elsewhere: RCSB PDB 5IZV · PDBe 5IZV · UniProt Q5ZUV9
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