MolNFT v1 · #122783 · protein
Crystal structure of a C-terminal proteolytic fragment of an outer surface protein from borrelia burgdorferi
5IZT: “Crystal structure of a C-terminal proteolytic fragment of an outer surface protein from borrelia burgdorferi”. X-ray diffraction, 2 pockets (best druggability 0.69). MolNFT v1 #122783 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5IZT
- Type
- protein
- Length
- 418 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Outer surface protein
- UniProt
- O50955
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 77% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Outer surface protein | protein | 211 | 77% helix, 1% strand | O50955 |
| B | Outer surface protein | protein | 207 | 77% helix, 1% strand | O50955 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 661 | 0.69 | 0.77 | 55 | empty |
| 2 | 126 | 0.40 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 652 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 5IZT · Crystal structure of a C-terminal proteolytic fragment of an outer surface protein from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O50955
- Elsewhere: RCSB PDB 5IZT · PDBe 5IZT · UniProt O50955
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