MolNFT v1 · #122412 · protein

Structure of the transmembrane domain of the transporter SLC26DG

5IOF · Sulphate transporter: “Structure of the transmembrane domain of the transporter SLC26DG”. X-ray diffraction, 17 pockets (best druggability 0.77). MolNFT v1 #122412 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5IOF
Type: protein
Length: 1,496 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sulphate transporter
UniProt: Q1J2S8
Pockets: 17 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Sulphate transporter	protein	374	70% helix, 2% strand	Q1J2S8

Pockets

17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1029	0.77	0.79	109	empty
2	994	0.77	0.79	112	empty
3	938	0.76	0.79	112	empty
4	858	0.75	0.78	101	empty
5	860	0.75	0.78	90	empty

Interfaces

3 interfaces between chains.

A–D · 795 Å² buried · 17 hydrogen bonds · protein-protein
B–C · 771 Å² buried · 17 hydrogen bonds · protein-protein
C–D · 145 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

5IOF · Structure of the transmembrane domain of the transporter SLC26Dg · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1J2S8
Elsewhere: RCSB PDB 5IOF · PDBe 5IOF · UniProt Q1J2S8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.