MolNFT v1 · #122307 · protein

Crystal structure of the dehydratase domain of rzxb from pseudomonas fluorescens

5IL6 · Polyketide SYNTHASE/NONRIBOSOMAL peptide synthetase hybrid…: “Crystal structure of the dehydratase domain of rzxb from pseudomonas fluorescens”. X-ray diffraction, 11 pockets (best druggability 0.73). MolNFT v1 #122307 on GenesisL1…

PDB: 5IL6
Type: protein
Length: 553 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polyketide SYNTHASE/NONRIBOSOMAL peptide synthetase hybrid rzxb
UniProt: Q4KCD8
Pockets: 11 · best druggability 0.73

Structure

x-ray diffraction · 2 distinct chains · 18% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polyketide SYNTHASE/NONRIBOSOMAL peptide synthetase hybrid rzxb	protein	275	19% helix, 42% strand	Q4KCD8
B	Polyketide SYNTHASE/NONRIBOSOMAL peptide synthetase hybrid rzxb	protein	278	18% helix, 43% strand	Q4KCD8

Pockets

11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	130	0.73	0.92	35	empty
2	106	0.68	0.91	28	empty
3	150	0.46	0.77	27	empty
4	107	0.44	0.78	20	empty
5	93	0.38	0.76	21	empty

Interfaces

1 interface between chains.

A–B · 618 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

5IL6 · Crystal structure of the dehydratase domain of RzxB from Pseudomonas fluorescens · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4KCD8
Elsewhere: RCSB PDB 5IL6 · PDBe 5IL6 · UniProt Q4KCD8

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