MolNFT v1 · #122246 · protein
Crystal structure of human serum albumin in the presence of 0.5 mm zinc at pH 9.0
5IJF: “Crystal structure of human serum albumin in the presence of 0.5 mm zinc at pH 9.0”. X-ray diffraction, 2 ligands (UNL, ZN), 7 pockets (best druggability 0.86). MolNFT v1 #122246 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5IJF
- Type
- protein
- Length
- 572 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serum albumin
- UniProt
- P02768
- Ligands
- UNL, ZN
- Pockets
- 7 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serum albumin | protein | 572 | 72% helix, 0% strand | P02768 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1046 | 0.86 | 0.87 | 106 | UNL |
| 2 | 101 | 0.65 | 0.89 | 21 | UNL |
| 3 | 145 | 0.63 | 0.85 | 22 | empty |
| 4 | 168 | 0.49 | 0.76 | 20 | empty |
| 5 | 213 | 0.48 | 0.75 | 36 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
- 5IJF · Crystal structure of Human Serum Albumin in the presence of 0.5 mM zinc at pH 9.0 · the same entry in another collection · chain A against A, TM-score 1.00
- P02768 · AlphaFold monomer V2.0 prediction for albumin (P02768) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02768
- Elsewhere: RCSB PDB 5IJF · PDBe 5IJF · UniProt P02768
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