MolNFT v1 · #122189 · protein
Crystal structure of bovine Fab B11
5IHU · Bovine Fab B11 light chain: “Crystal structure of bovine Fab B11”. X-ray diffraction, 4 pockets (best druggability 0.50). MolNFT v1 #122189 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5IHU
- Type
- protein
- Length
- 486 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bovine Fab B11 light chain; Bovine Fab B11 heavy chain
- Pockets
- 4 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | Bovine Fab B11 light chain | protein | 213 | 7% helix, 52% strand | — |
| H | Bovine Fab B11 heavy chain | protein | 273 | 5% helix, 49% strand | — |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 317 | 0.50 | 0.73 | 36 | empty |
| 2 | 102 | 0.39 | 0.76 | 24 | empty |
| 3 | 54 | 0.37 | 0.80 | 18 | empty |
| 4 | 54 | 0.26 | 0.73 | 13 | empty |
Interfaces
1 interface between chains.
- L–H · 2163 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 disulfide (disulfide).
Compared structures
- 5IHU · Crystal structure of bovine Fab B11 · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5IHU · PDBe 5IHU
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