MolNFT v1 · #122118 · protein

X-ray structure of hsa-myr-KP1019

5IFO · Serum albumin: “X-ray structure of hsa-myr-KP1019”. X-ray diffraction, 2 ligands (MYR, RU), 9 pockets (best druggability 0.87). MolNFT v1 #122118 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5IFO
Type: protein
Length: 582 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Serum albumin
UniProt: P02768
Ligands: MYR, RU
Pockets: 9 · best druggability 0.87

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Serum albumin	protein	582	72% helix, 0% strand	P02768

Ligands and binding sites

MYR · Myristic acid · ligand · 6 copies · chains A
RU · Ruthenium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	615	0.87	0.92	68	MYR
2	622	0.87	0.92	72	RU, MYR
3	287	0.75	0.87	26	MYR
4	210	0.69	0.86	32	MYR
5	185	0.60	0.82	24	empty

Modifications

Observed in the structure: 17 disulfide (disulfide).

Compared structures

5IFO · X-ray structure of HSA-Myr-KP1019 · the same entry in another collection · chain A against A, TM-score 1.00
P02768 · AlphaFold monomer V2.0 prediction for albumin (P02768) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02768
Elsewhere: RCSB PDB 5IFO · PDBe 5IFO · UniProt P02768

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.