MolNFT v1 · #121812 · protein

Crystal structure of C-terminal variant 2 of chaetomium thermophilum acetyl-CoA carboxylase

5I6G · Acetyl-CoA carboxylase-like PROTEIN,ACETYL-CoA carboxylase…: “Crystal structure of C-terminal variant 2 of chaetomium thermophilum acetyl-CoA carboxylase”. X-ray diffraction, 20 pockets (best druggability 0.83). MolNFT v1 #121812 on…

PDB: 5I6G
Type: protein
Length: 2,058 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acetyl-CoA carboxylase-like PROTEIN,ACETYL-CoA carboxylase- like protein
UniProt: G0S3L5
Pockets: 20 · best druggability 0.83

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Acetyl-CoA carboxylase-like PROTEIN,ACETYL-CoA carboxylase- like protein	protein	1028	37% helix, 20% strand	G0S3L5
B	Acetyl-CoA carboxylase-like PROTEIN,ACETYL-CoA carboxylase- like protein	protein	1030	37% helix, 21% strand	G0S3L5

Pockets

20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.83	0.94	30	empty
2	879	0.82	0.84	62	empty
3	299	0.79	0.90	45	empty
4	277	0.79	0.90	37	empty
5	457	0.74	0.83	44	empty

Interfaces

1 interface between chains.

A–B · 6831 Å² buried · 51 hydrogen bonds · protein-protein

Compared structures

5I6G · Crystal structure of C-terminal variant 2 of Chaetomium thermophilum acetyl-CoA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S3L5
Elsewhere: RCSB PDB 5I6G · PDBe 5I6G · UniProt G0S3L5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.