MolNFT v1 · #121811 · protein

Crystal structure of C-terminal variant 1 of chaetomium thermophilum acetyl-CoA carboxylase

5I6F · Acetyl-CoA carboxylase-like protein: “Crystal structure of C-terminal variant 1 of chaetomium thermophilum acetyl-CoA carboxylase”. X-ray diffraction, 20 pockets (best druggability 0.85). MolNFT v1 #121811 on GenesisL1: 3D…

PDB: 5I6F
Type: protein
Length: 2,092 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acetyl-CoA carboxylase-like protein
UniProt: G0S3L5
Pockets: 20 · best druggability 0.85

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Acetyl-CoA carboxylase-like protein	protein	1044	36% helix, 19% strand	G0S3L5
B	Acetyl-CoA carboxylase-like protein	protein	1048	36% helix, 20% strand	G0S3L5

Pockets

20 pockets found on a 1 Å grid, 17 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	359	0.85	0.94	34	empty
2	922	0.83	0.85	61	empty
3	308	0.80	0.91	47	empty
4	304	0.77	0.88	41	empty
5	384	0.73	0.84	49	empty

Interfaces

1 interface between chains.

A–B · 7153 Å² buried · 54 hydrogen bonds · protein-protein

Compared structures

5I6F · Crystal structure of C-terminal variant 1 of Chaetomium thermophilum acetyl-CoA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S3L5
Elsewhere: RCSB PDB 5I6F · PDBe 5I6F · UniProt G0S3L5

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