MolNFT v1 · #121800 · protein
Crystal structure of the insertion loop deletion mutant of the RNA- dependent RNA polymerase of a human picorbirnavirus
5I62 · Potential RNA-dependent RNA polymerase: “Crystal structure of the insertion loop deletion mutant of the RNA- dependent RNA polymerase of a human…”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #121800 on…
- PDB
- 5I62
- Type
- protein
- Length
- 507 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Potential RNA-dependent RNA polymerase
- EC
- 2.7.7.48
- UniProt
- Q50LE4
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Potential RNA-dependent RNA polymerase (EC 2.7.7.48) | protein | 507 | 49% helix, 15% strand | Q50LE4 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1027 | 0.70 | 0.75 | 97 | empty |
| 2 | 57 | 0.67 | 0.95 | 17 | empty |
| 3 | 55 | 0.41 | 0.81 | 15 | empty |
| 4 | 71 | 0.34 | 0.75 | 16 | empty |
Compared structures
- 5I62 · Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q50LE4
- Elsewhere: RCSB PDB 5I62 · PDBe 5I62 · UniProt Q50LE4
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