MolNFT v1 · #121779 · protein

Ecoli global domain 245-586

5I5H · Inner membrane protein yejm: “Ecoli global domain 245-586”. X-ray diffraction, 3 pockets (best druggability 0.46). MolNFT v1 #121779 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5I5H
Type: protein
Length: 327 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Inner membrane protein yejm
UniProt: P0AD27
Pockets: 3 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inner membrane protein yejm	protein	327	36% helix, 22% strand	P0AD27

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	87	0.46	0.81	17	empty
2	57	0.31	0.76	21	empty
3	77	0.30	0.73	16	empty

Compared structures

5I5H · Ecoli global domain 245-586 · the same entry in another collection · chain A against A, TM-score 1.00
P0AD27 · AlphaFold monomer V2.0 prediction for inner membrane protein yejm (P0AD27) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AD27
Elsewhere: RCSB PDB 5I5H · PDBe 5I5H · UniProt P0AD27

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