MolNFT v1 · #12166 · DNA

Structure of the human G-quadruplex reveals a novel topology

1K8P · 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3': “Structure of the human G-quadruplex reveals a novel topology”. X-ray diffraction, 2 ligands (K, NA). MolNFT v1 #12166 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1K8P
Type: DNA
Length: 24 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3'
Ligands: K, NA

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	5'-D((BRU)PAPGPGPGP(BRU)PTPAPGPGPGPT)-3'	dna	12	—	—

Ligands and binding sites

K · Potassium ion · metal · 2 copies · chains A, B
NA · Sodium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 416 Å² buried · 21 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 4 modified (nucleotide modification).

Compared structures

1K8P · Structure of the Human G-quadruplex reveals a novel topology · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1K8P · PDBe 1K8P

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