MolNFT v1 · #121641 · protein
Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from burkholderia vietnamiensis in complex with uridine-5'-diphosphate- glucose
5I1F · UTP--glucose-1-phosphate uridylyltransferase: “Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from burkholderia vietnamiensis in complex…”. X-ray diffraction, 3 ligands (UPG, MG, CL), 3 pockets (best druggability…
- PDB
- 5I1F
- Type
- protein
- Length
- 290 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UTP--glucose-1-phosphate uridylyltransferase
- EC
- 2.7.7.9
- UniProt
- A4JT02
- Ligands
- UPG, MG, CL
- Pockets
- 3 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) | protein | 290 | 41% helix, 25% strand | A4JT02 |
Ligands and binding sites
- UPG · Uridine-5'-diphosphate-glucose · ligand · chains A
- MG · Magnesium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 453 | 0.72 | 0.82 | 40 | UPG, MG, CL |
| 2 | 80 | 0.43 | 0.80 | 22 | empty |
| 3 | 51 | 0.31 | 0.77 | 12 | empty |
Compared structures
- 5I1F · Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4JT02
- Elsewhere: RCSB PDB 5I1F · PDBe 5I1F · UniProt A4JT02
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