MolNFT v1 · #121506 · protein

Crystal structure of Z,Z-farnesyl diphosphate synthase (D71M and E75A mutants) from the wild tomato solanum habrochaites

5HXN · (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic: “Crystal structure of Z,Z-farnesyl diphosphate synthase (D71M and E75A mutants) from the wild tomato solanum…”. X-ray diffraction, 2 pockets (best druggability 0.63). MolNFT v1…

PDB: 5HXN
Type: protein
Length: 220 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
EC: 2.5.1.92
UniProt: B8XA40
Pockets: 2 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	(2Z,6Z)-farnesyl diphosphate synthase, chloroplastic (EC 2.5.1.92)	protein	220	48% helix, 15% strand	B8XA40

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	162	0.63	0.85	22	empty
2	55	0.28	0.74	13	empty

Compared structures

5HXN · Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M and E75A mutants) from the… · the same entry in another collection · chain A against A, TM-score 1.00
B8XA40 · AlphaFold monomer V2.0 prediction for (2Z,6Z)-farnesyl diphosphate synthase… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8XA40
Elsewhere: RCSB PDB 5HXN · PDBe 5HXN · UniProt B8XA40

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