MolNFT v1 · #121485 · protein
Crystal structure of unknown function protein DFER_1899 fromdyadobacter fermentans dsm 18053
5HX0 · Uncharacterized protein DFER_1899: “Crystal structure of unknown function protein DFER_1899 fromdyadobacter fermentans dsm 18053”. X-ray diffraction, 7 pockets (best druggability 0.70). MolNFT v1 #121485 on GenesisL1: 3D structure…
- PDB
- 5HX0
- Type
- protein
- Length
- 729 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein DFER_1899
- UniProt
- C6VW01
- Pockets
- 7 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein DFER_1899 | protein | 365 | 3% helix, 51% strand | C6VW01 |
| B | Uncharacterized protein DFER_1899 | protein | 364 | 2% helix, 51% strand | C6VW01 |
Ligands and binding sites
- GOL · Glycerol · additive · 4 copies · chains A, B
- ACT · Acetate ion · additive · 3 copies · chains A, B
- PGE · Triethylene glycol · additive · 2 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 629 | 0.70 | 0.78 | 71 | empty |
| 2 | 370 | 0.67 | 0.80 | 30 | empty |
| 3 | 345 | 0.65 | 0.80 | 27 | empty |
| 4 | 280 | 0.60 | 0.78 | 30 | ACT, PGE |
| 5 | 262 | 0.59 | 0.79 | 29 | PG4, ACT, GOL |
Interfaces
1 interface between chains.
- A–B · 1386 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 5HX0 · Crystal structure of unknown function protein Dfer_1899 fromDyadobacter fermentans DSM… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6VW01
- Elsewhere: RCSB PDB 5HX0 · PDBe 5HX0 · UniProt C6VW01
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.