MolNFT v1 · #121026 · DNA
Cocrystal structure of an anti-parallel DNA G-quadruplex and a tetra- quinoline foldamer
5HIX · Dimeric G-quadruplex: “Cocrystal structure of an anti-parallel DNA G-quadruplex and a tetra- quinoline foldamer”. X-ray diffraction, 2 ligands (61Q, K). MolNFT v1 #121026 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5HIX
- Type
- DNA
- Length
- 24 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dimeric G-quadruplex
- Ligands
- 61Q, K
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Dimeric G-quadruplex | dna | 12 | — | — |
Ligands and binding sites
- 61Q · 4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-nitroquinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinoline-2-carboxylic acid · ligand · chains A
- K · Potassium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 810 Ų buried · 62 hydrogen bonds · nucleic-nucleic
Compared structures
- 5HIX · Cocrystal structure of an anti-parallel DNA G-quadruplex and a tetra-Quinoline Foldamer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5HIX · PDBe 5HIX
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