MolNFT v1 · #120822 · protein

Crystal structure of free-codv.

5HCG · Codv heavy-chain: “Crystal structure of free-codv.”. X-ray diffraction, 5 pockets (best druggability 0.72). MolNFT v1 #120822 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5HCG
Type: protein
Length: 659 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Codv heavy-chain; Codv light chain
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
H	Codv heavy-chain	protein	332	5% helix, 52% strand	—
L	Codv light chain	protein	327	4% helix, 47% strand	—

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1005	0.72	0.76	95	empty
2	114	0.36	0.73	23	empty
3	86	0.35	0.75	20	empty
4	78	0.35	0.76	18	empty
5	97	0.32	0.72	24	empty

Interfaces

1 interface between chains.

H–L · 3100 Å² buried · 34 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

5HCG · Crystal structure of free-codv. · the same entry in another collection · chain H against H, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5HCG · PDBe 5HCG

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