MolNFT v1 · #120774 · protein

Crystal structure of chaetomium thermophilum NUP170 sol

5HB1 · Nucleoporin NUP170: “Crystal structure of chaetomium thermophilum NUP170 sol”. X-ray diffraction, 6 pockets (best druggability 0.45). MolNFT v1 #120774 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5HB1
Type: protein
Length: 742 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoporin NUP170
UniProt: G0S7B6
Pockets: 6 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoporin NUP170	protein	742	74% helix, 2% strand	G0S7B6

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.45	0.78	18	empty
2	122	0.42	0.75	17	empty
3	50	0.40	0.82	13	empty
4	108	0.38	0.75	20	empty
5	91	0.37	0.75	19	empty

Compared structures

5HB1 · Crystal structure of Chaetomium thermophilum Nup170 SOL · the same entry in another collection · chain A against A, TM-score 1.00
G0S7B6 · AlphaFold monomer V2.0 prediction for nucleoporin NUP170 (G0S7B6) · a predicted model of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S7B6
Elsewhere: RCSB PDB 5HB1 · PDBe 5HB1 · UniProt G0S7B6

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