MolNFT v1 · #120772 · protein

Structure of chaetomium thermophilum NUP170 ctd

5HAZ · Nucleoporin NUP170: “Structure of chaetomium thermophilum NUP170 ctd”. X-ray diffraction, 1 ligand (NA), 8 pockets (best druggability 0.51). MolNFT v1 #120772 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5HAZ
Type: protein
Length: 551 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoporin NUP170
UniProt: G0S7B6
Ligands: NA
Pockets: 8 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoporin NUP170	protein	551	72% helix, 0% strand	G0S7B6

Ligands and binding sites

NA · Sodium ion · metal · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	173	0.51	0.78	24	empty
2	86	0.37	0.75	12	empty
3	82	0.36	0.76	18	empty
4	51	0.35	0.79	14	empty
5	56	0.30	0.75	15	empty

Compared structures

5HAZ · Structure of Chaetomium thermophilum Nup170 CTD · the same entry in another collection · chain A against A, TM-score 1.00
G0S7B6 · AlphaFold monomer V2.0 prediction for nucleoporin NUP170 (G0S7B6) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S7B6
Elsewhere: RCSB PDB 5HAZ · PDBe 5HAZ · UniProt G0S7B6

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