MolNFT v1 · #120743 · protein
Crystal structure of the LTBP1 leukotriene D4 complex
5HA0 · Lipocalin ai-4: “Crystal structure of the LTBP1 leukotriene D4 complex”. X-ray diffraction, 1 ligand (LTD), 1 pocket (best druggability 0.75). MolNFT v1 #120743 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5HA0
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipocalin ai-4
- UniProt
- Q7YT09
- Ligands
- LTD
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipocalin ai-4 | protein | 156 | 8% helix, 42% strand | Q7YT09 |
Ligands and binding sites
- LTD · (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 399 | 0.75 | 0.85 | 44 | LTD |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 5HA0 · Crystal structure of the LTBP1 leukotriene d4 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7YT09
- Elsewhere: RCSB PDB 5HA0 · PDBe 5HA0 · UniProt Q7YT09
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