MolNFT v1 · #120577 · protein
Crystal structure of cellulase from antarctic springtail, cryptopygus antarcticus
5H4U · Endo-beta-1,4-glucanase: “Crystal structure of cellulase from antarctic springtail, cryptopygus antarcticus”. X-ray diffraction, 8 pockets (best druggability 0.58). MolNFT v1 #120577 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5H4U
- Type
- protein
- Length
- 624 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endo-beta-1,4-glucanase
- UniProt
- D3GDK4
- Pockets
- 8 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 20% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Endo-beta-1,4-glucanase | protein | 208 | 20% helix, 29% strand | D3GDK4 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 247 | 0.58 | 0.79 | 30 | empty |
| 2 | 120 | 0.54 | 0.83 | 19 | empty |
| 3 | 229 | 0.51 | 0.76 | 30 | empty |
| 4 | 188 | 0.49 | 0.77 | 36 | empty |
| 5 | 177 | 0.49 | 0.77 | 30 | empty |
Interfaces
2 interfaces between chains.
- A–C · 356 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 213 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 21 disulfide (disulfide).
Compared structures
- 5H4U · Crystal structure of cellulase from Antarctic springtail, Cryptopygus antarcticus · the same entry in another collection · chain A against A, TM-score 1.00
- D3GDK4 · AlphaFold monomer V2.0 prediction for endoglucanase (D3GDK4) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3GDK4
- Elsewhere: RCSB PDB 5H4U · PDBe 5H4U · UniProt D3GDK4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.