MolNFT v1 · #120535 · protein

Crystal structure of arabidopsis SNC1 tir domain

5H3C · Protein suppressor of NPR1-1, constitutive 1: “Crystal structure of arabidopsis SNC1 tir domain”. X-ray diffraction, 2 pockets (best druggability 0.68). MolNFT v1 #120535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5H3C
Type: protein
Length: 303 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein suppressor of NPR1-1, constitutive 1
UniProt: O23530
Pockets: 2 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 56% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein suppressor of NPR1-1, constitutive 1	protein	158	55% helix, 15% strand	O23530
B	Protein suppressor of NPR1-1, constitutive 1	protein	145	57% helix, 15% strand	O23530

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	481	0.68	0.79	44	empty
2	103	0.40	0.76	20	empty

Interfaces

1 interface between chains.

A–B · 463 Å² buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

5H3C · Crystal structure of Arabidopsis SNC1 TIR domain · the same entry in another collection · chain A against A, TM-score 1.00
O23530 · AlphaFold monomer V2.0 prediction for protein suppressor of NPR1-1, constitutive 1… · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O23530
Elsewhere: RCSB PDB 5H3C · PDBe 5H3C · UniProt O23530

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.