MolNFT v1 · #120500 · protein
Crystal structure of saccharomyces cerevisiae OSH1 ank - NVJ1
5H2C · Oxysterol-binding protein homolog 1: “Crystal structure of saccharomyces cerevisiae OSH1 ank - NVJ1”. X-ray diffraction, 1 pocket (best druggability 0.39). MolNFT v1 #120500 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5H2C
- Type
- protein
- Length
- 267 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxysterol-binding protein homolog 1; Nucleus-vacuole junction protein 1
- UniProt
- P35845, P38881
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 2 distinct chains · 58% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxysterol-binding protein homolog 1 | protein | 251 | 59% helix, 1% strand | P35845 |
| B | Nucleus-vacuole junction protein 1 | protein | 16 | 50% helix, 0% strand | P38881 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.39 | 0.78 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 141 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 5H2C · Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1 · the same entry in another collection · chain A against A, TM-score 1.00
- P35845 · AlphaFold monomer V2.0 prediction for oxysterol-binding protein homolog 1 (P35845) · a predicted model of the same protein · chain A against A, TM-score 0.87
- P38881 · AlphaFold monomer V2.0 prediction for nucleus-vacuole junction protein 1 (P38881) · a predicted model of the same protein · chain B against A, TM-score 0.49
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35845
- Every structure of UniProt P38881
- Elsewhere: RCSB PDB 5H2C · PDBe 5H2C · UniProt P35845 · UniProt P38881
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