MolNFT v1 · #120498 · protein

Crystal structure of OSH1 ank domain from kluyveromyces lactis

5H2A · KLLA0C04147P: “Crystal structure of OSH1 ank domain from kluyveromyces lactis”. X-ray diffraction, 2 pockets (best druggability 0.57). MolNFT v1 #120498 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5H2A
Type: protein
Length: 528 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KLLA0C04147P
UniProt: Q6CUK7
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 58% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	KLLA0C04147P	protein	271	59% helix, 0% strand	Q6CUK7
B	KLLA0C04147P	protein	257	57% helix, 1% strand	Q6CUK7

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	189	0.57	0.80	28	empty
2	69	0.35	0.76	15	empty

Interfaces

1 interface between chains.

A–B · 702 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

5H2A · Crystal structure of Osh1 ANK domain from Kluyveromyces lactis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6CUK7
Elsewhere: RCSB PDB 5H2A · PDBe 5H2A · UniProt Q6CUK7

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