MolNFT v1 · #120479 · protein
CRISPR-associated protein
5H1P · CRISPR-associated endoribonuclease CAS2: “CRISPR-associated protein”. X-ray diffraction, 1 pocket (best druggability 0.51). MolNFT v1 #120479 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5H1P
- Type
- protein
- Length
- 169 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CRISPR-associated endoribonuclease CAS2
- EC
- 3.1.-.-
- UniProt
- D2UG58
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CRISPR-associated endoribonuclease CAS2 (EC 3.1.-.-) | protein | 86 | 35% helix, 31% strand | D2UG58 |
| B | CRISPR-associated endoribonuclease CAS2 (EC 3.1.-.-) | protein | 83 | 36% helix, 34% strand | D2UG58 |
Ligands and binding sites
- ACT · Acetate ion · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 148 | 0.51 | 0.79 | 26 | ACT |
Interfaces
1 interface between chains.
- A–B · 1400 Ų buried · 40 hydrogen bonds · protein-protein
Compared structures
- 5H1P · CRISPR-associated protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D2UG58
- Elsewhere: RCSB PDB 5H1P · PDBe 5H1P · UniProt D2UG58
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.