MolNFT v1 · #120326 · protein

Crystal structure of human RCC2

5GWN · Protein RCC2: “Crystal structure of human RCC2”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.76). MolNFT v1 #120326 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5GWN
Type: protein
Length: 427 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein RCC2
UniProt: Q9P258
Ligands: SO4
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 9% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein RCC2	protein	427	9% helix, 43% strand	Q9P258

Ligands and binding sites

SO4 · Sulfate ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	547	0.76	0.83	44	empty
2	163	0.48	0.77	25	SO4

Compared structures

5GWN · Crystal structure of human RCC2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9P258 · AlphaFold monomer V2.0 prediction for protein RCC2 (Q9P258) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9P258
Elsewhere: RCSB PDB 5GWN · PDBe 5GWN · UniProt Q9P258

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