MolNFT v1 · #120210 · protein
Crystal structure of the KIF19A motor domain complexed with mg-ADP
5GSZ · Kinesin-like protein KIF19: “Crystal structure of the KIF19A motor domain complexed with mg-ADP”. X-ray diffraction, 2 ligands (ADP, MG), 2 pockets (best druggability 0.40). MolNFT v1 #120210 on GenesisL1: 3D structure, binding…
- PDB
- 5GSZ
- Type
- protein
- Length
- 306 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kinesin-like protein KIF19
- UniProt
- Q99PT9
- Ligands
- ADP, MG
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Kinesin-like protein KIF19 | protein | 306 | 26% helix, 30% strand | Q99PT9 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.40 | 0.76 | 18 | empty |
| 2 | 81 | 0.37 | 0.77 | 20 | MG |
Compared structures
- 5GSZ · Crystal Structure of the KIF19A Motor Domain Complexed with Mg-ADP · the same entry in another collection · chain A against A, TM-score 1.00
- Q99PT9 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF19 (Q99PT9) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99PT9
- Elsewhere: RCSB PDB 5GSZ · PDBe 5GSZ · UniProt Q99PT9
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