MolNFT v1 · #119975 · protein
The structure of vibrio ANGUILLARUM775 angb-icl
5GLE · Ischorismate lyase: “The structure of vibrio ANGUILLARUM775 angb-icl”. X-ray diffraction, 4 pockets (best druggability 0.75). MolNFT v1 #119975 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5GLE
- Type
- protein
- Length
- 416 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ischorismate lyase
- UniProt
- Q6W4P9
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ischorismate lyase | protein | 208 | 38% helix, 17% strand | Q6W4P9 |
| B | Ischorismate lyase | protein | 208 | 38% helix, 18% strand | Q6W4P9 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 99 | 0.75 | 0.96 | 22 | empty |
| 2 | 89 | 0.75 | 0.96 | 22 | empty |
| 3 | 204 | 0.55 | 0.79 | 20 | empty |
| 4 | 79 | 0.32 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1445 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 5GLE · The structure of Vibrio anguillarum775 AngB-ICL · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6W4P9
- Elsewhere: RCSB PDB 5GLE · PDBe 5GLE · UniProt Q6W4P9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.