MolNFT v1 · #119955 · protein

Crystal structure of tripartite-type ABC transporter, macb from acinetobacter baumannii

5GKO · Macrolide export ATP-BINDING/PERMEASE protein macb: “Crystal structure of tripartite-type ABC transporter, macb from acinetobacter baumannii”. X-ray diffraction, 20 pockets (best druggability 0.82). MolNFT v1 #119955 on GenesisL1…

PDB: 5GKO
Type: protein
Length: 1,300 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Macrolide export ATP-BINDING/PERMEASE protein macb
EC: 3.6.3.-
UniProt: A0A0D8G707
Pockets: 20 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Macrolide export ATP-BINDING/PERMEASE protein macb (EC 3.6.3.-)	protein	650	48% helix, 20% strand	A0A0D8G707

Pockets

20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	902	0.82	0.84	72	empty
2	99	0.75	0.96	29	empty
3	300	0.70	0.84	36	empty
4	470	0.64	0.77	45	empty
5	374	0.62	0.77	36	empty

Interfaces

1 interface between chains.

A–B · 2272 Å² buried · 26 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 40 modified (engineered).

Compared structures

5GKO · Crystal structure of tripartite-type ABC transporter, MacB from Acinetobacter baumannii · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0D8G707
Elsewhere: RCSB PDB 5GKO · PDBe 5GKO · UniProt A0A0D8G707

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